Title: Phytochemical studies and antimicrobial activity of babool seeds
Authors: Srivastava, M; Kumar, G; Mohan, R; Malhotra, S
Abstract: The antibacterial activity of seed extracts
of A. nilotica, P. juliflora and L.
leucocephala was determined in vitro using disc diffusion method against
different bacterial strains viz. S.
aureus, E. coli, P. aeruginosa, K. pneumonia and S. typhi.
Dried powder was subjected to successive hot extraction method to obtain
various extracts viz. n-hexane, chloroform, acetone, alcohol and water. Assay
was performed at a dose of 100 mg/ml, compared to standard Amikacin (30 mg/ml).
Maximum inhibition zone of 10 mm was observed by acetone, alcohol and water
extract of A. nilotica against E. coli, S. typhi, S. aureus and P.
aeruginosa respectively. P. juliflora
extracts showed activity (8 mm) against S.
aureus and S. typhi only. In L.
leucocephala, n-hexane, alcohol and water extractive showed more prominent
activity (8 mm). E. coli is neither
inhibited by P. juliflora nor by L. does leucocephala extract. Hence a
considerable zone of inhibition was observed by all the three babool species,
among which A. nilotica exhibit most
significant activity against tested strains followed by L. leucocephala and P.
juliflora. The study prospects for detailed investigation on isolation and
activity guided fractionation of babool seed extracts and their utilization as
potential antimicrobials.
Page(s): 724-728
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